The fluid dynamic and shear environment in the NASA/JSC rotating-wall perfused-vessel bioreactor

Characterization of the osteoblast-like

Characterization of the osteoblast-like cell phenotype under microgravity conditions in the NASA-approved rotating wall vessel bioreactor (RWV)

✍ Nadia Rucci; Silvia Migliaccio; Bianca Maria Zani; Anna Taranta; Anna Teti 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 419 KB

## Abstract Weightlessness induces bone loss in humans and animal models. We employed the NASA‐approved Rotating Wall Vessel bioreactor (RWV) to develop osteoblast‐like cell cultures under microgravity and evaluate osteoblast phenotype and cell function. Rat osteoblast‐like cell line (ROS.SMER#14)