𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The first synthesis of optically pure biscarbazoles and determination of their absolute configurations

✍ Scribed by Guoqiang Lin; Aimin Zhang

Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
242 KB
Volume
40
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

Optically pure dimeric O-demethylmurrayafoline A (1) and its 6,6' -dirnethoxyl analog 2 were synthesized via the resolution of their corresponding camphorsulfonates of the racemates. The absolute configurations of (+)-1, (+)-2 and (-)-I, (-)-2 were assigned as (aR) and (aS), respectively, by the X-ray analysis and CD spectrum.

πŸ“œ SIMILAR VOLUMES

Determination of the absolute configurat
Determination of the absolute configuration of partly fluorinated allylic alcohols; the first synthesis of optically pure 1,2-difluoroallylic alcohols
✍ Yumiko Takagi; Takiko Nakatani; Toshiyuki Itoh*; Toshiyuki Oshiki* πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 French βš– 118 KB

Optically active 1,1,2-trifluoro-or 1,2-difluoroallylic alcohols were prepared via a lipase-catalyzed reaction and their absolute configuration was determined by an X-ray crystallographic analysis of the corresponding ferrocene ester along with the refined Mosher method (the Kusumi-Ohtani method).

Synthesis of chiral isoquinuclidines and
Synthesis of chiral isoquinuclidines and determination of their absolute configuration
✍ M. Mehmandoust; C. Marazano; R. Singh; B. Gillet; M. CΓ©sario; J.-L. Fourrey; B.C πŸ“‚ Article πŸ“… 1988 πŸ› Elsevier Science 🌐 French βš– 282 KB

A route to 1,2\_dihydropyridines &-substituted with chiral auxiliaries has been developed starting from commercially available chiral amines. Cycloaddition between these dihydropyridines and methyl acrylate gave, in moderate d.e., isoquinuclidines of good enantiomeric purity whose absolute configura