The first synthesis of (±)-brevione B, an allelopathic agent isolated from Penicillium sp.
✍ Scribed by Hirosato Takikawa; Manabu Hirooka; Mitsuru Sasaki
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 147 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Breviones A E (1 5), allelopathic agents isolated from Penicillium brevicompactum Dierckx, are structurally unique pentacyclic or hexacyclic diterpenoid derivatives. The first synthesis of brevione B (2) was achieved by employing the double S N 2%-type tandem reaction as a key step.
📜 SIMILAR VOLUMES
+)-Brevione A, the first member of a novel family of bioactive spiroditerpenoids, a potential allelopathic agent, has been isolated from the ethyl acetate active fractions of the aqueous acetone extracts of semi-solid fermented Penicillium brevicompactum Dierckx. The structure displays the novel spi