A crystalline tetrabutylammonium salt of 7-hydroxy-4-methylcoumarin was prepared and shown to contain two coumarin residues for each ammonium group. Condensation of this salt with the glycosyl chloride of methyl 5-acetamido-4,7,8,9tetra-~-acetyl-3,5-ddeoxy-~-D~~ycero-D-gu~acto-2-non~opyr~osona~ in d
The first synthesis of a C-7 nitrogen-containing sialic acid analogue, 5-acetamido-7-azido-3,5,7-trideoxy-d-glycero-d-galacto-2-nonulopyranosonic acid (7-azido-7-deoxy-Neu5Ac)
β Scribed by David C.M. Kong; Mark von Itzstein
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 173 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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A study aimed at developing an enantioselective synthesis of the title compound 23, a 2-monodeoxy analogue of the naturally occurring ()-2-keto-3-deoxy-d-glycero-d-galacto-2-nononic acid (KDN), is reported. From d-mannose as starting material, the chiral 1,3-diene 10, activated by a silyloxy substit
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