The first stereocontrolled synthesis of isoflavanones
✍ Scribed by Jose L. Vicario; Dolores Badı́a; Esther Domı́nguez; Mónica Rodrı́guez; Luisa Carrillo
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 61 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
The first asymmetric synthesis of isoflavanones has been performed employing a stereocontrolled aldol reaction between an (S,S)-(+)-pseudoephedrine arylacetamide and para-formaldehyde as the key step.
📜 SIMILAR VOLUMES
Isoflavanones 4a-d have been prepared in a stereocontrolled fashion using (S,S)-(+)-pseudoephedrine as a chiral auxiliary. The employed synthetic pathway consists of only four steps and involves initial formation of the stereogenic centre via diastereoselective aldol reaction of pseudoephedrine aryl
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