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The first approach to kinamycin antibiotics: Synthesis of kinafluorenone scaffold

โœ Scribed by Dipakranjan Mal; Nirmal K. Hazra


Book ID
103410180
Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
98 KB
Volume
37
Category
Article
ISSN
0040-4039

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The first total synthesis of Manamycin A, as its (+)-enantiomer, is reported. The synthetic route feattwes an asymmetric epoxidation (based on Wynberg's chirai phase transfer methodology) for the preparation of the key epoxyquinol nucleus, and a further demonstration of the utility of the Stifle rea