The first and convenient synthesis of acyclic dienediynes related to neocarzinostatin chromophore

✍ Scribed by Murielle Bujard; Fabiola Ferri; Mouaˆd Alami

• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 223 KB
• Volume: 39
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(98)00693-5

✦ Synopsis

A stereocontrolled and flexible synthetic approach to acyclic (E,E) and (Z,E)-dienediynes, related to the neocarzinostatin chromophore 5, from readily available stannylated chlorodienes 1 and dienynes 2 is described.