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Synthesis and cytotoxicity of the acyclic (E)- and (Z)-dienediyne systems related to neocarzinostatine chromophore

✍ Scribed by Kazuhiko Nakatani; Katsuko Arai; Noriaki Hirayama; Fuyuhiko Matsuda; Shiro Terashima


Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
275 KB
Volume
31
Category
Article
ISSN
0040-4039

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A stereocontrolled and flexible synthetic approach to acyclic (E,E) and (Z,E)-dienediynes, related to the neocarzinostatin chromophore 5, from readily available stannylated chlorodienes 1 and dienynes 2 is described.