The Feulgen-Stained Somatic Cell Nucleus as a Homogeneously Absorbing Object

Detection of 11q13 amplification as the

Detection of 11q13 amplification as the origin of a homogeneously staining region in small cell lung cancer by chromosome microdissection

✍ Jia Xu; Tina Tyan; Edward Cedrone; Niramol Savaraj; Nancy Wang 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 640 KB

Chromosomal homogeneous staining region (hsr), which is a cytogenetic indication of gene amplification, was found in the pleural effusion (BHII) of a patient with small cell lung cancer (SCLC) after failure of multiple drug treatments. Amplification of band I I q I 3 was identified as the origin of