The failure of female cells to present in vitro the male H-Y antigen for secondary cytotoxic T-cell responses
โ Scribed by Giovanni Biasi; Francesco Dazzi; Bruce Loveland; Rosanna Rivarollo; Geoffrey Asherson
- Publisher
- Springer-Verlag
- Year
- 1985
- Tongue
- English
- Weight
- 288 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0093-7711
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๐ SIMILAR VOLUMES
The histocompatibility (H) system comprises a large number of loci responsible for acceptance and rejection of both neoplastic and normal tissue. The H-2 locus is the mouse major histocompatibility complex (MHC). H-2 class I and class II alloantigens exhibit high antigenic strength, while the remain
## Abstract The present study investigates the role of nonโHโ2 genes in controlling generation of the Hโ2โrestricted, T cellโmediated cytotoxic response against trinitrophenyl (TNP)โmodified syngeneic cells (TNPโself). Spleen cells from C3H/He (Hโ2^k^) or B10.BR (Hโ2^k^) normal mice or from mice pr