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The extracellular regulated kinases (ERK) 1/2 mediate cannabinoid-induced inhibition of gap junctional communication in endothelial cells

✍ Scribed by R P Brandes; R Popp; G Ott; D Bredenkötter; C Wallner; R Busse; I Fleming

Book ID
110007349
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
317 KB
Volume
136
Category
Article
ISSN
0007-1188

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The AU565 breast carcinoma cell line was used to determine the role of the extracellular-regulated kinase (ERK) pathway in mediating Heregulin␤1 (HRG␤1)-induced mammary cell differentiation. ERK activation remained elevated for 2 h following high doses of HRG which induce differentiation. In contras