The expressions of Pin1, β-catenin and cyclin D1 in elderly lung carcinomas and their significance
✍ Scribed by Jian Liu; Jun Zhao; Jianming Yang
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 150 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1610-1979
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## Abstract ## Background. Nuclear/cytoplasmic accumulation of β‐catenin is mainly regulated by its degradation, which is initiated by interaction with adenomatous polyposis coli (APC) protein. Accumulation of β‐catenin activates the transcription of 1 of the target oncogenic genes, cyclin D1, in