## Abstract Light information reaches the suprachiasmatic nucleus (SCN) through a subpopulation of retinal ganglion cells. Previous work raises the possibility that brainโderived neurotrophic factor (BDNF) and its highโaffinity receptor TrkB may be important as modulators of this excitatory input i
The excitoprotective effect of N-methyl-d-aspartate receptors is mediated by a brain-derived neurotrophic factor autocrine loop in cultured hippocampal neurons
โ Scribed by Xueying Jiang; Feng Tian; Karen Mearow; Peter Okagaki; Robert H. Lipsky;
- Book ID
- 111178969
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 244 KB
- Volume
- 94
- Category
- Article
- ISSN
- 0022-3042
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## Abstract Several neurotrophic factors, including brainโderived neurotrophic factor (BDNF), and neurotransmitters, such as glutamate, may influence neuronal apoptotic death. Rat cerebellar granule neurons (CGN) cultured in low potassium (5 or 10 mM KCl) for more than 5 days in vitro (DIV) die apo