Growth factors, including members of the neurotrophin gene family, play a central role in the regulation of neuronal survival and differentiation during development. In addition to these relatively long-term actions of neurotrophins, recent studies have shown that these factors also rapidly modulate
Brain derived neurotrophic factor induction of N-methyl-D-aspartate receptor subunit NR2A expression in cultured rat cortical neurons
β Scribed by Daniel L Small; Christine L Murray; Geoffrey A.R Mealing; Michael O Poulter; Alastair M Buchan; Paul Morley
- Book ID
- 117476975
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 91 KB
- Volume
- 252
- Category
- Article
- ISSN
- 0304-3940
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Light information reaches the suprachiasmatic nucleus (SCN) through a subpopulation of retinal ganglion cells. Previous work raises the possibility that brainβderived neurotrophic factor (BDNF) and its highβaffinity receptor TrkB may be important as modulators of this excitatory input i
## Abstract Brainβderived neurotrophic factor (BDNF) promotes a variety of neuromodulatory processes during development as well as in adulthood. This neurotrophin has been associated with synaptic plasticity, suggesting that its regulation may represent one of the mechanisms through which psychotro
Evidence is accumulating that glutamate-mediated excitotoxicity plays an important role in neuronal degeneration in Parkinson's disease (PD). In addition, alterations in excitatory amino acid neurotransmission in the basal ganglia contribute to the clinical manifestations of motor dysfunction. Howev