We have examined the relative levels of oestrogen receptor beta (ERβ€) mRNA in 94 breast cancer specimens using a semi-quantitative RT-PCR procedure. We correlated its expression with ERβ£ and various clinical, pathological and biochemical features of the disease. The level of ERβ€ mRNA expression in t
β¦ LIBER β¦
The evolving role of oestrogen receptor beta in clinical breast cancer
β Scribed by Valerie Speirs
- Book ID
- 120699402
- Publisher
- BioMed Central
- Year
- 2008
- Tongue
- English
- Weight
- 41 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1465-5411
- DOI
- 10.1186/bcr2140
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The first studies of oestrogen receptor (ER) focused on measurements of levels in breast cancers and relationship to hormonal response, but the introduction of antibodies which can be used on fixed tissue has meant that ER can be studied in detail in normal and precancerous tissue. Cloning and seque