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The evolution of viruses. Competition between horizontal and vertical transmission of mobile genes

✍ Scribed by Martin Nowak


Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
608 KB
Volume
150
Category
Article
ISSN
0022-5193

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✦ Synopsis


The transmission dynamics of viruses in a replicating cell population is investigated, assuming that viral mutants differ in their efficiencies of horizontal and vertical transmission. As a generic result we find that competition between such different viral strategies need not select for increasing basic reproductive rates. We illustrate evolutionary trajectories that lead to increased viral latency even at the expense of lower basic reproductive rates and lower equilibrium abundance. In some cases oscillations in the prevalence of different mutants are obtained.


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