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The evaluation of low-dose cytarabine in the treatment of myelodysplastic syndromes: A phase-III intergroup study

✍ Scribed by K. B. Miller; K. Kyungmann; F. S. Morrison; J. N. Winter; J. M. Bennett; R. S. Neiman; D. R. Head; P. A. Cassileth; M. J. O'Connell

Publisher: Springer
Year: 1992
Tongue: English
Weight: 744 KB
Volume: 65
Category: Article
ISSN: 0939-5555
DOI: 10.1007/bf01703109

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## Abstract ## BACKGROUND: Clofarabine is a nucleoside analog with activity in myeloid malignancies. Experience in myelodysplastic syndrome (MDS) is limited. ## METHODS: The goal of this study was to evaluate the activity and safety of 2 different doses (15 mg/m^2^ vs 30 mg/m^2^ daily × 5 days)