Twenty-five adult patients with refractory acute lymphocytic leukemia received salvage therapy with mitoxantrone 5 mg/m2 intravenously over 1 hour daily for 5 days and cytosine arabinoside 3 g/m2 intravenously over 2 hours every 12 hours for six doses. Overall, nine patients (36%) achieved complete
High-dose cytosine arabinoside in the treatment of preleukemic disorders: A leukemia intergroup study
β Scribed by H. D. Preisler; A. Raza; M. Barcos; N. Azarnia; R. Larson; G. Browman; I. Walker; H. Grunwald; P. D'Arrigo; A. Stein; M. Bloom; J. Goldberg; A. Gottlieb; J. Bennett; J. Kirshner; R. Priore
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 245 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0361-8609
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Department of Heremission whereas 5 patients (23%) succumbed to early death and 3 patients (14%) matology and Oncology, Go Β¨ttingen, Germany. did not respond. Blood counts recovered at a median of 33.5 days after the start 2 Westfa Β¨lische Wilhelms University, Department of treatment and complete r
Problem. Therapy of children with relapsed acute lymphoblastic leukemia (ALL) not achieving a second remission (CR2) after an initial reinduction attempt is problematic. Methods. 52 children with ALL in first relapse received high-dose cytosine arabinoside and L-asparaginase (HDAraC/L-Asp) after fa