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The estrogen receptor agonist/antagonist temoxifen improves endothelial function in postmenopausal women

✍ Scribed by J. Lekakis; C. Papamichael; P. Athanasiadis; N. Desses; C. Vemmos; A. Gika; A. Voutsas; S. Stamatelopoulos

Book ID
118588995
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
148 KB
Volume
31
Category
Article
ISSN
1558-3597

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## Abstract ## Objective Increased endothelin activity may play a role in the pathogenesis of vascular injury, a primary feature of systemic sclerosis (SSc; scleroderma). Our goal was to test the hypothesis that treatment with the oral endothelin receptor antagonist bosentan might improve vascular