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Daily administration of the TP receptor antagonist terutroban improved endothelial function in high-cardiovascular-risk patients with atherosclerosis

✍ Scribed by Pierre-François Lesault; Laurent Boyer; Gabriel Pelle; Ala Covali-Noroc; Dominique Rideau; Servais Akakpo; Emmanuel Teiger; Jean-Luc Dubois-Randé; Serge Adnot

Book ID: 108642661
Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 952 KB
Volume: 71
Category: Article
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.2010.03858.x

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✍ P. P. Sfikakis; C. Papamichael; K. S. Stamatelopoulos; D. Tousoulis; K. G. Fragi 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 102 KB 👁 2 views

## Abstract ## Objective Increased endothelin activity may play a role in the pathogenesis of vascular injury, a primary feature of systemic sclerosis (SSc; scleroderma). Our goal was to test the hypothesis that treatment with the oral endothelin receptor antagonist bosentan might improve vascular