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The Enzymic and Chemical Synthesis of Ursodeoxycholic and Chenodeoxycholic Acid from Cholic Acid

โœ Scribed by Sutherland, J. Derek; Macdonald, Ian A.; Forrest, Thomas P.


Book ID
121513681
Publisher
Informa UK (Taylor & Francis)
Year
1982
Tongue
English
Weight
431 KB
Volume
12
Category
Article
ISSN
0032-7484

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Labeled bile acids V: Deuterium and carb
โœ Chee Kong Lai; Chang Yon Byon; Marcel Gut; Danuta Mostowicz; Warren G. Anderson ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 364 KB

This paper describes a general, simple and short procedure for the introduction o f stable isotopes (deuterium and carbon-13) to the side chain of bile acids. The bisnorcholyl aldehydes of cholic and chenodeoxycholic acids are key intermediates, while the isotope is introduced by the Wittig condensa