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The Enzymatic Synthesis of Guanosine Diphosphate Colitose by a Mutant Strain of Escherichia coli

✍ Scribed by Edward C. Heath and Alan D. Elbein


Book ID
123657273
Publisher
National Academy of Sciences
Year
1962
Tongue
English
Weight
335 KB
Volume
48
Category
Article
ISSN
0027-8424

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A new class of mutants of E. coli exhibiting altered metabolism of ppGpp and pppGpp has been isolated, and mapped at a locus designated gpp, near min 83 on the genetic map. These mutants accumulate elevated levels of pppGpp during amino acid starvation or carbon source downshift, and exhibit a reduc