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Synthesis of guanosine 5′-diphosphate, 3′-diphosphate in spot mutants of Escherichia coli

✍ Scribed by Herman A. De Boer; Wicher J. Weyer; Johan G. De Boer; Sicco Van Der Heide; Max Gruber


Book ID
115746683
Publisher
Elsevier Science
Year
1977
Weight
427 KB
Volume
474
Category
Article
ISSN
0005-2787

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Mutants of Escherichia coli defective in
✍ Somerville, C. R. ;Ahmed, A. 📂 Article 📅 1979 🏛 Springer 🌐 English ⚖ 791 KB

A new class of mutants of E. coli exhibiting altered metabolism of ppGpp and pppGpp has been isolated, and mapped at a locus designated gpp, near min 83 on the genetic map. These mutants accumulate elevated levels of pppGpp during amino acid starvation or carbon source downshift, and exhibit a reduc