The enzymatic conversion of exomethylene cephalosporin c into deacetyl cephalosporin c and the role of molecular oxygen in cephalosporin c biosynthesis
β Scribed by Jack E. Baldwin; Robert M. Adlington; Nicholas P. Crouch; Christopher J. Schofield
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 531 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4020
No coin nor oath required. For personal study only.
β¦ Synopsis
Acetyl Coeaxymc A 4 -CeplMqcfia c Intact cell experiment8 have demonstrated that %,3!,-"C-valine (5a) gave 4-LaC-cepha108Porin C (6a).* whilst 22.32-*'C-valine (5b) gave 3-methylene-"C-Cephaloeporin C (6b).' 58)AI "CH,; B -"CW,
π SIMILAR VOLUMES
## Abstract The main drawback in the production of 7βaminocephalosporanic acid (7βACA) at the industrial level is the inactivation of the enzymes implicated in the process due to the presence of hydrogen peroxide during the reaction. As an alternative, we have developed the conversion of cephalospo
Bioprocesses using filamentous fungi immobilized in inert supports present many advantages when compared to conventional free cell processes. However, assessment of the real advantages of the unconventional process demands a rigorous study of the limitations to diffusional mass transfer of the reage