The Environmental Basis of the Down Syndrome Phenotype
โ Scribed by Burton L. Shapiro
- Book ID
- 115266300
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 632 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0012-1622
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๐ SIMILAR VOLUMES
## Abstract Down syndrome (DS) is the most common genetic cause of significant intellectual disability in the human population, occurring in roughly 1 in 700 live births. The ultimate cause of DS is trisomy of all or part of the set of genes located on chromosome 21. How this trisomy leads to the p
Maternal serum alpha-fetoprotein (MS-AFP), human chorionic gonadotropin (hCG), and unconjugated estriol (uE3) are routinely measured in the second trimester ("triple" test) and combined with maternal age to evaluate risk for fetal Down syndrome. Triple test results and clinical findings were retrosp