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TRANSLOCATION-CARRYING PHENOTYPICALLY NORMAL MALES AND THE DOWN SYNDROME

โœ Scribed by Forssman, H.; Lehmann, O.


Book ID
122707154
Publisher
The Lancet
Year
1961
Tongue
English
Weight
160 KB
Volume
277
Category
Article
ISSN
0140-6736

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Molecular analysis of chromosome 21 in a
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Down syndrome (DS) is caused in most cases by the presence of an extra chromosome 21. It has been shown that the DS phenotype is produced by duplication of only a small part of the long arm of chromosome 21, the 21q22 region, including and distal to locus D21S55. We present molecular investigations