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The enthalpy change in the hydrolysis of the phosphate esters of myo-inositol

✍ Scribed by Raison, John K.; Evans, William J.


Book ID
122836877
Publisher
Elsevier Science
Year
1968
Tongue
English
Weight
258 KB
Volume
170
Category
Article
ISSN
0304-4165

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Inositol monophosphatase plays a pivotal role in the biosynthesis of secondary messengers and is believed to be a target for lithium therapy. It is established how a lithium ion works in inhibiting the enzyme but details of the mechanism for the direct magnesium ion activated hydrolysis of the subst