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The endozepine ODN stimulates polyphosphoinositide metabolism in rat astrocytes

✍ Scribed by C. Patte; H. Vaudry; L. Desrues; P. Gandolfo; I. Strijdveen; M. Lamacz; M.C. Tonon


Book ID
115930602
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
368 KB
Volume
362
Category
Article
ISSN
0014-5793

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Astroglial cells synthesize and release endozepines, a family of neuropeptides derived from diazepam-binding inhibitor (DBI). The authors have recently shown that b-amyloid peptide (Ab) stimulates DBI gene expression and endozepine release. The purpose of this study was to determine the mechanism of