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Beta-amyloid peptides stimulate endozepine biosynthesis in cultured rat astrocytes

✍ Scribed by Tursonjan Tokay; Olfa Masmoudi; Pierrick Gandolfo; Jérôme Leprince; Georges Pelletier; Hubert Vaudry; Marie-Christine Tonon

Book ID
111178874
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
454 KB
Volume
94
Category
Article
ISSN
0022-3042

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✍ Tursonjan Tokay; Raya Hachem; Olfa Masmoudi-Kouki; Pierrick Gandolfo; Laurence D 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 365 KB 👁 1 views

Astroglial cells synthesize and release endozepines, a family of neuropeptides derived from diazepam-binding inhibitor (DBI). The authors have recently shown that b-amyloid peptide (Ab) stimulates DBI gene expression and endozepine release. The purpose of this study was to determine the mechanism of