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The emerging role of epigenetic modifications and chromatin remodeling in spinal muscular atrophy

โœ Scribed by Sebastian Lunke; Assam El-Osta

Book ID
111181507
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
323 KB
Volume
109
Category
Article
ISSN
0022-3042

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## Abstract The hereditary neurodegenerative disease spinal muscular atrophy (SMA) with childhood onset is one of the most common genetic causes of infant mortality. The disease is characterized by selective loss of spinal cord motor neurons leading to muscle atrophy and is the result of mutations