The emerging CK2 interactome: insights into the regulation and functions of CK2
โ Scribed by Laszlo Gyenis; David W. Litchfield
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 434 KB
- Volume
- 316
- Category
- Article
- ISSN
- 0300-8177
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## Abstract The regulatory subunit of protein kinase CK2, designated CK2ฮฒ, exists both free in cells and in complexes with the CK2 catalytic subunits. Growing evidence suggests that CK2ฮฒ has functions dependent and independent of the CK2 catalytic subunits. There have been indications that CK2ฮฒ has
Protein kinase CK2 is a ubiquitous eukaryotic ser/thr protein kinase. The active holoenzyme is a heterotetrameric protein composed of catalytic (โฃ and โฃะ) and regulatory (โค) subunits that phosphorylates many different protein substrates and appears to be involved in the regulation of cell division.
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