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Protein kinase CK2, an important regulator of the inflammatory response?

✍ Scribed by Nishi N. Singh; Dipak P. Ramji

Publisher: Springer
Year: 2008
Tongue: English
Weight: 264 KB
Volume: 86
Category: Article
ISSN: 0946-2716
DOI: 10.1007/s00109-008-0352-0

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Protein kinase CK2 is a ubiquitous eukaryotic ser/thr protein kinase. The active holoenzyme is a heterotetrameric protein composed of catalytic (␣ and ␣Ј) and regulatory (␤) subunits that phosphorylates many different protein substrates and appears to be involved in the regulation of cell division.