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The elucidation of the primary structure of the hypothalamic thyroid stimulating hormone releasing factor of ovine origin by means of mass spectrometry

✍ Scribed by Dominic M. Desiderio Jr.; Roger Burgus; Thomas F. Dunn; Wylie Vale; Roger Guillemin; Darrell N. Ward

Book ID
102552252
Publisher
John Wiley and Sons
Year
1971
Tongue
English
Weight
479 KB
Volume
5
Category
Article
ISSN
1076-5174

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✦ Synopsis

Abstract

This paper illustrates the role that mass spectrometry played in the first elucidation of the primary structure of a hypothalamic releasing factor. It has been demonstrated that ovine TRF has the structure 2‐pyrrolidone‐5‐carboxylyl‐histidyl‐proline amide.

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