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The Electronic Structure of the Flavin Cofactor in DNA Photolyase

✍ Scribed by Weber, Stefan; Möbius, Klaus; Richter, Gerald; Kay, Christopher W. M.


Book ID
126865479
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
219 KB
Volume
123
Category
Article
ISSN
0002-7863

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Photolyase is an enzyme that catalyzes photorepair of thymine dimers in UV damaged DNA by electron-transfer reaction. We docked a thymine dimer to photolyase catalytic site, using crystal structure coordinates of the substrate-free enzyme from Escherichia coli, studied molecular dynamics of the syst