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The efficacy of tyrosine kinase inhibitors on human pancreatic cancer cell lines1

✍ Scribed by Robert Saeid Farivar; James Gardner-Thorpe; Hiromichi Ito; Hassan Arshad; Michael J Zinner; Stanley W Ashley; Edward E Whang

Book ID
117169471
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
137 KB
Volume
115
Category
Article
ISSN
0022-4804

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Breast cancers frequently over-express a number of growth factor receptors. In addition, elevated src family kinase activity is present in a percentage of these neoplasms and has been implicated in signal transduction in these cells. Therefore, inhibiting tyrosine kinase activity is a potential appr