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The effects of taurine on pharmacologically induced myotonia

✍ Scribed by Dr. Diana Conte Camerino; Dr. Annamaria De Luca; Dr. Mercede Mambrini; Dr. Ermanno Ferrannini; Dr. Flavia Franconi; Dr. Alberto Giotti; Dr. Shirley H. Bryant

Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
569 KB
Volume
12
Category
Article
ISSN
0148-639X

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## Abstract The effect of intraperitoneally injected taurine against the convulsive activity induced by 4‐aminopyridine (4‐AP) was studied in 12‐ to 15‐day‐old mice. At a dose of 2.6 mg/kg, taurine increased the latency of clonic seizures from 7 to 20 minutes, reduced the incidence of tonic seizure