Differential effects of gamma-hexachlorocyclohexane (lindane) on pharmacologically-induced seizures

Effects of Psychopharmacologic Agents on

Effects of Psychopharmacologic Agents on Experimentally-Induced Seizures in Mice**Received August 21, 1959, from the Departments of Pharmacology, University of Utah, College of Pharmacy and College of Medicine, Salt Lake City.

✍ Fink, Gregory B. ;Swinyard, Ewart A. 📂 Article 📅 1960 🏛 Elsevier ⚖ 384 KB

Of seven psychopharmacologic drugs screened by live assay procedures, only meprobamate and phenaglycodol exhibited significant anticonvulsant activity. Chlorpromazine, promazine, reserpine, and hydroxyzine lowered the threshold for minimal seizures variously induced, whereas t d u p r o m a z i n e