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The effects of ‘Step-down’ on RNA metabolism in HeLa cells

✍ Scribed by M.E. Bramwell; S.D. Handmaker


Book ID
118876623
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
570 KB
Volume
91
Category
Article
ISSN
0014-4827

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Incubation of HeLa cells at 42°C results in pronounced inhibition of the accumulation of 18s and 28s ribosomal RNA (rRNA) and non-heat shock polyadenylated messenger RNA (mRNA) in the cytoplasm. Accumulation of transfer RNA and 5s ribosomal RNA is not affected. Transcription of rRNA precursor is red