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Effect of puromycin on RNA synthesis in HeLa cells

โœ Scribed by Taiki Tamaoki; Gerald C. Mueller


Book ID
118848199
Publisher
Elsevier Science
Year
1963
Tongue
English
Weight
308 KB
Volume
11
Category
Article
ISSN
0006-291X

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Incubation of HeLa cells at 42ยฐC results in pronounced inhibition of the accumulation of 18s and 28s ribosomal RNA (rRNA) and non-heat shock polyadenylated messenger RNA (mRNA) in the cytoplasm. Accumulation of transfer RNA and 5s ribosomal RNA is not affected. Transcription of rRNA precursor is red