✦ LIBER ✦

The effects of inhibiting cytochrome P450 3A, p-glycoprotein, and gastric acid secretion on the oral bioavailability of methadone in dogs

✍ Scribed by B. KUKANICH; B. D. X. LASCELLES; A. M. AMAN; K. L. MEALEY; M. G. PAPICH

Book ID: 108884952
Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 128 KB
Volume: 28
Category: Article
ISSN: 0140-7783
DOI: 10.1111/j.1365-2885.2005.00681.x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The effect of P-glycoprotein and cytochr

The effect of P-glycoprotein and cytochrome P450 3a on the oral bioavailability of vinorelbine in mice

✍ Rogier R. Press; Tessa Buckle; Jos H. Beijnen; Olaf van Tellingen 📂 Article 📅 2005 🏛 Springer 🌐 English ⚖ 285 KB

The influence of modulation of P-glycopr

The influence of modulation of P-glycoprotein and /or Cytochrome P450 3A on the pharmacokinetics and pharmacodynamics of orally administered morphine in dogs

✍ C. GADEYNE; S. VAN der HEYDEN; F. GASTHUYS; S. CROUBELS; S. SCHAUVLIEGE; I. POLI 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 274 KB

Impact of gastric acid suppressants on c

Impact of gastric acid suppressants on cytochrome P450 3A4 and P-glycoprotein: Consequences for FK506 assimilation

✍ Lemahieu, Wim P.D.; Maes, Bart D.; Verbeke, Kristin; Vanrenterghem, Yves 📂 Article 📅 2005 🏛 Nature Publishing Group 🌐 English ⚖ 187 KB

Effects of baicalein on the pharmacokine

Effects of baicalein on the pharmacokinetics of tamoxifen and its main metabolite, 4-hydroxytamoxifen, in rats: Possible role of cytochrome p450 3A4 and P-glycoprotein inhibition by baicalein

✍ Cheng Li; Minhee Kim; HongSeok Choi; JunShik Choi 📂 Article 📅 2011 🏛 Springer 🌐 English ⚖ 283 KB

Effects of myricetin on the bioavailabil

Effects of myricetin on the bioavailability of doxorubicin for oral drug delivery in Rats: Possible role of CYP3A4 and P-glycoprotein inhibition by myricetin

✍ Sang-Joon Choi; Sang-Chul Shin; Jun-Shik Choi 📂 Article 📅 2011 🏛 Springer 🌐 English ⚖ 405 KB

Investigation of the coordinated functio

Investigation of the coordinated functional activities of cytochrome P450 3A4 and P-glycoprotein in limiting the absorption of xenobiotics in Caco-2 cells

✍ Christine D.H. Tran; Peter Timmins; Barbara R. Conway; William J. Irwin 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 233 KB

The coordination of the functional activities of intestinal CYP3A4 and P-gp in limiting the absorption of xenobiotics in Caco-2 cells was investigated. Growing Caco-2 cells were exposed to increasing concentrations of doxorubicin (1±2 mM) in plastic ¯asks to encourage a subpopulation of cells, that