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The effects of drugs on activity in two strains of rats selectively bred for high and low emotionality

✍ Scribed by Keir Gregory; B.D. Gupta; H.C. Holland


Book ID
118933948
Publisher
Elsevier Science
Year
1967
Tongue
English
Weight
320 KB
Volume
6
Category
Article
ISSN
0024-3205

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The action of 20 mg/kg, i.p. of the drug prenylamine (Segontin) upon two forms of exploratory activity was examined in strains of rats selectively bred for differences in emotionality. The drug significantly depressed ambulation in an Open Field arena compared to placebo and although not apparently