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The effects of chronic uremia on glucagon binding and action in isolated rat hepatocytes

✍ Scribed by Thomas G. Helinek; Scott Sadel; Jose F. Caro


Book ID
118948855
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
650 KB
Volume
33
Category
Article
ISSN
1532-8600

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✍ R. Pagani; M. T. PortolΓ©s; A. M. Municio πŸ“‚ Article πŸ“… 1984 πŸ› Springer 🌐 English βš– 598 KB

Number and affinity constant of low affinity binding sites of insulin and glucagon to isolated hepatocytes decreased when the cells were incubated with Escherichia coli 0111:B4 lipopolysaccharide. This effect agrees with a non-specific binding of lipopolysaccharide to hepatocytes, similar to the wel