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The effects of acute and chronic dexamethasone administration on insulin binding to isolated rat hepatocytes and adipocytes

✍ Scribed by Jerrold M. Olefsky; Jennifer Johnson; Francis Liu; Phyllis Jen; Gerald M. Reaven

Book ID
118947466
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
830 KB
Volume
24
Category
Article
ISSN
1532-8600

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Number and affinity constant of low affinity binding sites of insulin and glucagon to isolated hepatocytes decreased when the cells were incubated with Escherichia coli 0111:B4 lipopolysaccharide. This effect agrees with a non-specific binding of lipopolysaccharide to hepatocytes, similar to the wel