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The effects of chemical modification on the refolding transition of α-chymotrypsin

✍ Scribed by Jim Stoesz; Rufus W. Lumry


Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
909 KB
Volume
10
Category
Article
ISSN
0301-4622

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The effectiveness of the covalent modification of a-chymotrypsin with methoxy poly(ethylene glycol) (PEG) to afford its stabilization during encapsulation in poly(lactic-co-glycolic) acid (PLGA) microspheres by a solid-in-oil-in-water method was investigated. a-Chymotrypsin was chemically modified w