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The effects of aqueous extracts of Tetracarpidium conophorum seeds on the hormonal parameters of male guinea pigs

✍ Scribed by AW Obianime; FI Uche

Book ID
119646204
Publisher
Medknow Publications
Year
2010
Tongue
English
Weight
324 KB
Volume
3
Category
Article
ISSN
1995-7645

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The hot water extract (HWE) of the seed of Mucuna pruriens dose-dependently contracted the guinea-pig ileum. The ED 50 and pD 2 values for the HWE was lower than those of ACh and histamine. Cyproheptadine and promethazine (10 ng/mL) significantly antagonized the effects of histamine, 5-hydroxytrypta