The effects of 4-aminopyridine on motor evoked potentials in multiple sclerosis
β Scribed by Kazuo Fujihara; Tasuku Miyoshi
- Book ID
- 119470028
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 122 KB
- Volume
- 159
- Category
- Article
- ISSN
- 0022-510X
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Paired transcranial magnetic stimulation was applied in 33 multiple sclerosis (MS) patients and in 21 healthy controls. A major abnormality was found in latency of the second motor-evoked potential in MS patients. At interstimulus intervals of 75, 100, and 150 ms the central motor conduction time (C
## Abstract We tested cortical motor evoked potentials (cMEPs) as a quantitative marker for in vivo monitoring of corticospinal tract damage in a murine multiple sclerosis model (experimental autoimmune encephalomyelitis, EAE). The cMEPs, previously standardized in naive C57BL/6 developing and adul