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The effect of α-amanitin on RNA synthesis in rat liver mitochondria

✍ Scribed by C. Saccone; R. Gallerani; M.N. Gadaleta; M. Greco

Book ID: 115902272
Publisher: Elsevier Science
Year: 1971
Tongue: English
Weight: 223 KB
Volume: 18
Category: Article
ISSN: 0014-5793
DOI: 10.1016/0014-5793(71)80481-7

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## Abstract Investigations were conducted to test the effects of α‐amanitin on RNA synthesis in preimplantation mouse embryos. Exposure of embryos in culture to 1–100 μg/ml α‐amanitin produced a dose‐ and time‐dependent suppression of total RNA synthesis as measured by incorporation of [^3^H]uridin