𝔖 Bobbio Scriptorium
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The Effect of α-Amanitin on Nucleic Acid Synthesis in Preimplantation Mouse Embryos

✍ Scribed by C.M. WARNER; T.F. HEARN

Book ID
115110747
Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
754 KB
Volume
7
Category
Article
ISSN
0301-4681

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## Abstract Actinomycin D and α‐amanitin (an inhibitor of RNA polymerase II) were used to determine the effect of inhibiting RNA synthesis during pre‐implantation mouse embryogenesis. Actinomycin D (0.01 μg/ml) was an effective inhibitor of blastulation and of cleavage from the 1 cell stage on. The