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The effect of wetting agents on the dissolution of indomethacin solid dispersion systems

โœ Scribed by Hilton, Jane E.; Summers, M.P.


Book ID
123057151
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
767 KB
Volume
31
Category
Article
ISSN
0378-5173

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The effects of sodium deoxycholate on the dissolution of indomethacin metal complexes were investigated. At pH 7.2, the dissolution of copper-indomethacin was very slow, while the dissolution of zinc-indomethacin was higher but less than that of indomethacin. In the presence of 5 mg of sodium deoxyc