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Effect of polymer type on the dissolution profile of amorphous solid dispersions containing felodipine

โœ Scribed by Hajime Konno; Tetsurou Handa; David E. Alonzo; Lynne S. Taylor

Book ID
115542793
Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
257 KB
Volume
70
Category
Article
ISSN
0939-6411

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๐Ÿ“œ SIMILAR VOLUMES

Influence of different polymers on the c
Influence of different polymers on the crystallization tendency of molecularly dispersed amorphous felodipine
โœ Hajime Konno; Lynne S. Taylor ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 353 KB

The ability of various polymers to inhibit the crystallization of amorphous felodipine was studied in amorphous molecular dispersions. Spin-coated films of felodipine with poly(vinylpyrrolidone) (PVP), hydroxypropylmethylcellulose acetate succinate (HPMCAS), and hydroxypropylmethylcellulose (HPMC) w

Effect of temperature and moisture on th
Effect of temperature and moisture on the miscibility of amorphous dispersions of felodipine and poly(vinyl pyrrolidone)
โœ Patrick J. Marsac; Alfred C. F. Rumondor; David E. Nivens; Umesh S. Kestur; Lia ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 541 KB

The physical stability of amorphous molecular level solid dispersions will be influenced by the miscibility of the components. The goal of this work was to understand the effects of temperature and relative humidity on the miscibility of a model amorphous solid dispersion. Infrared spectroscopy was